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  "Package": "CLME",
  "Title": "Constrained Inference for Linear Mixed Effects Models",
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  "Date": "2026-04-04",
  "Description": "Estimation and inference for linear models where some or\nall of the fixed-effects coefficients are subject to order\nrestrictions. This package uses the robust residual bootstrap\nmethodology for inference, and can handle some structure in the\nresidual variance matrix.",
  "Authors@R": "c(person(\"Casey M.\"  , \"Jelsema\", email=\"jelsema.casey@gmail.com\", role=c(\"aut\", \"cre\") ),\nperson(\"Shyamal D.\", \"Peddada\", role=\"aut\" ))",
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  "BugReports": "https://github.com/jelsema/CLME/issues",
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  "Repository": "https://jelsema.r-universe.dev",
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    "minque",
    "model_terms_clme",
    "random.effects",
    "resid_boot",
    "shiny_clme",
    "shinyServer_clme",
    "shinyUI_clme",
    "VarCorr",
    "w.stat",
    "w.stat.ind"
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        "data.frame"
      ],
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        "id",
        "fid",
        "lfgr",
        "age",
        "loc",
        "bmi",
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        "race",
        "vol"
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      "table": true,
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    },
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      "file": "rat.blood.csv.gz",
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      ],
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        "time",
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        "sex",
        "wbc",
        "rbc",
        "hgb",
        "hct",
        "spun",
        "mcv",
        "mch",
        "mchc",
        "plts"
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      "table": true,
      "tojson": true
    }
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      "page": "CLME-package",
      "title": "Constrained inference for linear mixed models.",
      "topics": [
        "CLME-package",
        "CLME"
      ]
    },
    {
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      "title": "Akaike information criterion",
      "topics": [
        "AIC.clme",
        "AIC.summary.clme"
      ]
    },
    {
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      "topics": [
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        "BIC.summary.clme"
      ]
    },
    {
      "page": "clme",
      "title": "Constrained Inference for Linear Mixed Effects Models",
      "topics": [
        "clme"
      ]
    },
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      "title": "Constrained EM algorithm for linear fixed or mixed effects models.",
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        "clme_em",
        "clme_em_fixed",
        "clme_em_mixed"
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      "topics": [
        "clme_resids"
      ]
    },
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        "confint.summary.clme"
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        "coef.summary.clme",
        "coefficients.clme",
        "coefficients.summary.clme",
        "fixed.effects",
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    },
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